omicron incubation period cdc

doi:10.1001/jamanetworkopen.2021.11182, Feldstein LR, Tenforde MW, Friedman KG, et al. The Lancet Haematology. Late Conditions Diagnosed 1-4 Months Following an Initial Coronavirus Disease 2019 (COVID-19) Encounter: A Matched-Cohort Study Using Inpatient and Outpatient Administrative Data-United States, 1 March-30 June 2020. New loss of taste or smell . Jul 16 2020;doi:10.1093/cid/ciaa1012, Kompaniyets L, Pennington AF, Goodman AB, et al. MMWR Morb Mortal Wkly Rep. Sep 10 2021;70(36):1249-1254. doi:10.15585/mmwr.mm7036e1, Cloete J, Kruger A, Masha M, et al. TaqPath COVID-19 Multiplex Diagnostic Solution. MMWR Morb Mortal Wkly Rep. Apr 30 2021;70(17):644-650. doi:10.15585/mmwr.mm7017e3, Chevinsky JR, Tao G, Lavery AM, et al. study . 2021:n385. Saving Lives, Protecting People, Itako Public Health Center of Ibaraki Prefectural Government, Ibaraki, Japan (T. Ogata), Public Health Center of Neyagawa City, Osaka, Japan (H. Tanaka), National Institute of Infectious Diseases. The mean virus incubation period during the SARS-CoV-2 Omicron BA.5-dominant period in Japan was 2.6 (95% CI 2.5-2.8) days, which was less than during the Delta-dominant period. Many of the first reported cases of Omicron variant infection appear to be mild (7), although as with all variants, a lag exists between infection and more severe outcomes, and symptoms would be expected to be milder in vaccinated persons and those with previous SARS-CoV-2 infection than in unvaccinated persons. 2021/08/01/ 2021;46:520-524. doi:https://doi.org/10.1016/j.ajem.2020.11.006, Nasiri N, Sharifi H, Bazrafshan A, Noori A, Karamouzian M, Sharifi A. Ocular Manifestations of COVID-19: A Systematic Review and Meta-analysis. Shortness of breath or difficulty breathing. Risk of long COVID associated with delta versus omicron variants of SARS-CoV-2. Some experts say the omicron variant has "sped up" timing for what many have come to know with COVID, including the incubation period, or the time between exposure and the start of symptoms. Data from December 2021 suggests that Omicrons average incubation period is around two to four days, which would mean that symptoms may develop faster after exposure compared to other variants. Jul 1 2021;18:E66. MMWR Morb Mortal Wkly Rep. Jan 28 2022;71(4):132-138. doi:10.15585/mmwr.mm7104e2, Danza P, Koo TH, Haddix M, et al. Infectees exposed while eating do not normally wear masks and may share longer exposure times, so they might be exposed to a higher viral load than those exposed through conversations while wearing a mask. The information in this article is current as of the date listed, which means newer information may be available when you read this. We calculated the incubation period by using the calendar dates of contact and symptom onset, regardless of duration or number of contacts. Message not sent. Ogata T, Tanaka H. SARS-CoV-2 Incubation Period during the Omicron BA.5Dominant Period in Japan. Researchers say it's too early to know whether that shorter incubation period for omicron translates into earlier contagiousness. doi:http://dx.doi.org/10.15585/mmwr.mm7113e1, Pingali C, Meghani M, Razzaghi H, et al. The number of confirmed COVID-19 cases from July 4 through August 19, 2022, was 12,577 in the PHCs jurisdiction, which has a population of 265,000 persons (5). days (95% CI). We performed multivariate gamma regression analyses; transmission during shared meals (p = 0.03) and age of infector (p = 0.007) correlated significantly with incubation period (Table 2). 2022;6(5):294-302. doi:10.1016/s2352-4642(22)00027-x, Torjesen I. Covid-19: Omicron variant is linked to steep rise in hospital admissions of very young children. This is shorter than with Delta and earlier variants. People with COVID-19 may be asymptomatic or experience one or more of the following symptoms(5): The NIH COVID-19 Treatment Guidelinesgroup SARS-CoV-2 infection into five categories based on severity of illness: Studies have documented infection with SARS-CoV-2 in people who never develop symptoms (asymptomatic presentation) and in people who are asymptomatic when tested but then develop symptoms later (presymptomatic presentation). A new variant of SARS-CoV-2 (the virus that causes COVID-19), B.1.1.529 (Omicron) (1), was first reported to the World Health Organization (WHO) by South Africa on November 24, 2021. Clin Infect Dis. Update: Characteristics of Symptomatic Women of Reproductive Age with Laboratory-Confirmed SARS-CoV-2 Infection by Pregnancy Status - United States, January 22-October 3, 2020. doi:http://dx.doi.org/10.15585/mmwr.mm7121e1, Sudre CH, Murray B, Varsavsky T, et al. Fifth, the variant type was not confirmed by using genomic sequencing. MMWR Morb Mortal Wkly Rep. Jan 28 2022;71(4):146-152. doi:10.15585/mmwr.mm7104e4, Taylor CA, Whitaker M, Anglin O, et al. Shorter incubation period among unvaccinated Delta variant coronavirus disease 2019 patients in Japan. CDC: Study Finds A Shorter Incubation Period of 3 Days With Omicron, Compared to Delta. Virus Evol 2021;7:veab064. New England Journal of Medicine. SARS-CoV-2 B.1.1.529 (Omicron) Variant United States, December 18, 2021. In our study, we estimated the incubation period (period between virus exposure and symptom onset) of SARS-CoV-2 Omicron BA.5, determined potential correlations with demographic data and transmission settings, and compared the BA.5 subvariant with other subvariants. However . Oct 3 2022;75(Supplement_2):S303-s307. Current trends and geographical differences in therapeutic profile and outcomes of COVID-19 among pregnant women - a systematic review and meta-analysis. This system obtains genomic surveillance data from 1) National SARS-CoV-2 Strain Surveillance, 2) CDC-supported contracts with several commercial diagnostic laboratories, and 3) public repositories (the Global Initiative on Sharing Avian Influenza Data [GISAID] and the National Center for Biotechnology Information [NCBI]) of randomly sampled viruses with metadata tagging of sequences by various partners. The rapid emergence and worldwide detection of the SARS-CoV-2 Omicron variant underscores the importance of robust genomic surveillance systems and prompt information-sharing among global public health partners. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. The first limitation of our study is that the infector and infectee might have been mutually misclassified, leading to overestimation. Saving Lives, Protecting People. Sect. EClinicalMedicine. His interests focus on evaluating data on and responding to epidemics in the Itako PHC jurisdiction and Japan. Response to additional COVID-19 vaccine doses in people who are immunocompromised: a rapid review. . MMWR Morb Mortal Wkly Rep. Aug 5 2022;71(31):993-999. doi:10.15585/mmwr.mm7131a3, Zavala M, Ireland G, Amin-Chowdhury Z, Ramsay ME, Ladhani SN. CDC recommends prioritizing case investigation and contact tracing for confirmed COVID-19 cases attributed to the Omicron variant. Use of At-Home COVID-19 Tests United States, August 23, 2021March 12, 2022. Aug 4 2022;doi:10.1093/cid/ciac637, Levy M, Recher M, Hubert H, et al. The score is derived from an automated algorithm, and represents a weighted count of the amount of attention Altmetric picked up for a research output. Emerg Infect Dis. MMWR Morb Mortal Wkly Rep. Dec 31 2021;70(5152):1766-1772. doi:10.15585/mmwr.mm705152a3, Woodruff RC, Campbell AP, Taylor CA, et al. (1) A study conducted during high levels of Delta variant transmission reported an incubation period of 4.3 days, (2) and studies performed during high levels of Omicron variant transmission reported a median incubation period of 3-4 days. Of the 1,216 samples collected during January 3February 6 in Ibaraki, a total of 1,158 (95%) were negative for the SARS-CoV-2 spike protein mutation L452R (8). Among the 14 persons who were vaccinated and had received an additional dose, five had received the additional dose <14 days before symptom onset. JAMA Netw Open. The utility of iPhone oximetry apps: A comparison with standard pulse oximetry measurement in the emergency department. Characteristics of Persons Who Died with COVID-19 - United States, February 12-May 18, 2020. Its still important for everyone to get tested regularly if theyve been exposed to ensure that they are not inadvertently spreading the virus, especially since people are infectious before symptoms appear. You will be subject to the destination website's privacy policy when you follow the link. Data is collected weekly and does not include downloads and attachments. Fatigue. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. Atlanta, GA: US Department of Health and Human Services, CDC; 2021. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. Among these cases of COVID-19 attributed to the Omicron variant, 34 (79%) occurred inpersons whocompleted the primary series of an FDA-authorized or approved COVID-19 vaccine 14 days before symptom onset or receipt of a positive SARS-CoV-2 test result, including 14 who had received an additional or booster dose; five of the 14 persons had received the additional dose <14 days before symptom onset. Am J Obstet Gynecol MFM. For purposes of entry into the United States, vaccines accepted will include FDA approved or authorized and WHO Emergency Use Listing vaccines. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. Risk factors for illness severity among pregnant women with confirmed SARS-CoV-2 infection Surveillance for Emerging Threats to Mothers and Babies Network, 20 state, local, and territorial health departments, March 29, 2020 -January 8, 2021. medRxiv. Clin Infect Dis. How long are. The clinical presentation of COVID-19 ranges from asymptomatic to critical illness. National Institute for Communicable Diseases. Effectiveness of a Third Dose of Pfizer-BioNTech and Moderna Vaccines in Preventing COVID-19 Hospitalization Among Immunocompetent and Immunocompromised Adults - United States, August-December 2021. Post-COVID-19 Symptoms and Conditions Among Children and Adolescents - United States, March 1, 2020-January 31, 2022. You can review and change the way we collect information below. But some scientists who've studied Omicron and. Effect of Covid-19 Vaccination on Transmission of Alpha and Delta Variants. Eur J Obstet Gynecol Reprod Biol. There are arguments that could be made both towards shortening or lengthening, Weiss said. Clin Microbiol Infect. Of secondary cases, 90% had an incubation period of 6 days for Omicron and 7 days for Delta. JAMA Netw Open. Multisystem inflammatory syndrome in adults (MIS-A): case finding through systematic review of electronic medical records. Cookies used to make website functionality more relevant to you. May 2020;94:91-95. doi:10.1016/j.ijid.2020.03.017, Tenforde MW, Billig Rose E, Lindsell CJ, et al. Prevalence and clinical presentation of long COVID in children: a systematic review. Dermatology. CDC updates and shortens recommended isolation and quarantine period for general population. During December 18, 2021, 22 U.S. states reported at least one COVID-19 case attributed to the Omicron variant. Study: Newer COVID-19 Variants Have Shorter Incubation Periods. Lancet Respir Med. mmwrq@cdc.gov. Feb 2021;257:11-18. doi:10.1016/j.ejogrb.2020.11.068, Prabhu M, Cagino K, Matthews KC, et al. While long COVID, hospitalization, or death is less likely if a person is vaccinated, it is still possible and is not a risk that most of us want to take. CDC has developed a working case definition for MIS-A. The Lancet Child & adolescent health. Am J Transplant. Trends in Geographic and Temporal Distribution of US Children With Multisystem Inflammatory Syndrome During the COVID-19 Pandemic. Health and Human Services. Feb 1 2021;72(3):521-533. doi:10.1093/cid/ciaa828, Dubey P, Thakur B, Reddy S, et al. A shorter incubation suggests a shorter quarantine period for BA.5 than for other variants. COVID-19 Incidence and Death Rates Among Unvaccinated and Fully Vaccinated Adults with and Without Booster Doses During Periods of Delta and Omicron Variant Emergence - 25 U.S. Jurisdictions, April 4-December 25, 2021. Skin Manifestations Associated with COVID-19: Current Knowledge and Future Perspectives. Original Publication Date: January 31, 2023, Table of Contents Volume 29, Number 3March 2023. Jun 1 2021;4(6):e2111182. doi:10.1093/cid/ciab338, Wanga V, Chevinsky JR, Dimitrov LV, et al. BMC Infect Dis. Sep 13 2022;226(5):797-807. doi:10.1093/infdis/jiac118, Parker EPK, Desai S, Marti M, et al. Lancet Glob Health. BA.2 is a sub-variant of Omicron, which means it is likely that it has a shorter incubation period as well, Oller said. The rapid antigen test may help gauge infectiousness: If a person tests positive, they should consider themselves contagious, he added. May 2020;38(5):925-928. doi:10.1016/j.ajem.2019.07.020, Iuliano AD, Brunkard JM, Boehmer TK, et al. By Carla Delgado Preventing chronic disease. doi:10.1093/cid/ciab991, Davis HE, Assaf GS, McCorkell L, et al. Risk Factors for Intensive Care Unit Admission and In-hospital Mortality among Hospitalized Adults Identified through the U.S. Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization Surveillance Network (COVID-NET). COVID19 in childhood: Transmission, clinical presentation, complications and risk factors. 2020:1-7. doi:10.1080/14767058.2020.1793320, Grechukhina O, Greenberg V, Lundsberg LS, et al. Even if most infections are mild, a highly transmissible variant could result in enough cases to overwhelm health systems. N Engl J Med. World Health Organization. doi:10.1001/jamanetworkopen.2021.26456, Melgar M, Haston J, DeCuir J, et al. COVID Incubation Period Has Changed and Chicago's Top Doc Says That's 'Good News' During her Facebook Live last week, Chicago Department of Public Health Commissioner Dr. Allison Arwady. Cookies used to make website functionality more relevant to you. As of December 8, a total of 22 states had identified at least one Omicron variant case, including some that indicate community transmission. Cookies used to make website functionality more relevant to you. Implementation of concurrent prevention strategies, including vaccination, masking, increasing ventilation, testing, quarantine, and isolation, are recommended to slow transmission of SARS-CoV-2, including variants such as Omicron, and to protect against severe illness and death from COVID-19. 2022/09/15 2022;doi:10.1007/s00431-022-04600-x, Zimmermann P, Pittet LF, Curtis N. How Common is Long COVID in Children and Adolescents? 2021;237(1):1-12. doi:10.1159/000512932, Thompson HA, Mousa A, Dighe A, et al. Emerg Infect Dis. May 19 2022;386(20):1899-1909. doi:10.1056/NEJMoa2202826, Zambrano LD, Ellington S, Strid P, et al. How Does Omicron Compare to Previous Variants? He says multiple studies have shown that "there's very little, if any, transmission after day 10, regardless of the variant . When we fitted incubation period data from the BA.5dominant period to parametric distribution models, the Akaike information criterion for gamma distribution was smaller than that for Gaussian, lognormal, and Weibull distribution models. The CDC recently examined what happened to a Nebraska patient who was reportedly infected with the . You will be subject to the destination website's privacy policy when you follow the link. doi:10.1093/cid/ciab936, Patel P, DeCuir J, Abrams J, Campbell AP, Godfred-Cato S, Belay ED. According to the CDC, the incubation period for COVID is between two and 14 days, though the newest guidance from the agency suggests a quarantine of five days for those who are not boosted, but eligible or unvaccinated. Clinical Imaging. Furthermore, children usually have mild symptoms, and average viral shedding might be less than that of an adult (15). What we know about quarantine and isolation. doi:10.1001/jamanetworkopen.2021.43151, Kompaniyets L, Agathis NT, Nelson JM, et al. Feb 10 2022;386(6):509-520. doi:10.1056/NEJMoa2116044, Sjoding MW, Dickson RP, Iwashyna TJ, Gay SE, Valley TS. It appears that a person is likely to be most infectious one to two days before symptoms appear, which continues for a few days after the symptoms begin, Weiss said. Systematic review and meta-analysis of chest radiograph (CXR) findings in COVID-19. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. For those without symptoms, CDC guidance states they are considered contagious at least two days before their positive test. doi:10.1093/ofid/ofab428, Rader B.; Gertz AL, D.; Gilmer, M.; Wronski, L.; Astley, C.; Sewalk, K.; Varrelman, T.; Cohen, J.; Parikh, R.; Reese, H.; Reed, C.; Brownstein J. Compare this with Delta and other strains . The first U.S. case of COVID-19 attributed to the Omicron variant was detected on December 1, 2021. As of December 8, one of these pools was confirmed positive for Omicron, and four were pending. Waltham, MA: ThermoFisher Scientific; 2021. Pediatric Pulmonology. 2020/09/01/ 2020;98:180-186. doi:https://doi.org/10.1016/j.ijid.2020.06.052, Yang J, Zheng Y, Gou X, et al. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. 552a; 44 U.S.C. MMWR Morb Mortal Wkly Rep. Apr 8 2022;71(14):524-526. doi:10.15585/mmwr.mm7114a2, Slezak J, Bruxvoort K, Fischer H, Broder B, Ackerson B, Tartof S. Rate and severity of suspected SARS-Cov-2 reinfection in a cohort of PCR-positive COVID-19 patients. Read our. Effectiveness of two-dose vaccination with mRNA COVID-19 vaccines against COVID-19-associated hospitalizations among immunocompromised adults-Nine States, January-September 2021. The incubation period was shorter among patients who had transmission occur during shared meals and those with adult infectors. SARS-CoV-2 setting-specific transmission rates: a systematic review and meta-analysis. Annu Rev Med. Dec 23 2021;385(26):2487-2489. doi:10.1056/NEJMc2108120, Rossler A, Riepler L, Bante D, von Laer D, Kimpel J. SARS-CoV-2 Omicron Variant Neutralization in Serum from Vaccinated and Convalescent Persons. medRxiv. (15) Images of cutaneous findings in COVID-19 are available from the American Academy of Dermatology. Maternal, fetal and neonatal outcomes of large series of SARS-CoV-2 positive pregnancies in peripartum period: A single-center prospective comparative study. According to . Paediatric hospitalisations due to COVID-19 during the first SARS-CoV-2 omicron (B.1.1.529) variant wave in South Africa: a multicentre observational study. Accessed December 3, 2021. Impact of SARS-CoV-2 Delta variant on incubation, transmission settings and vaccine effectiveness: Results from a nationwide case-control study in France. A study of the Oslo Christmas party outbreak found the incubation period could be about three days, compared with 4.3 days for delta and five days for other variants. Serial Intervals and Household Transmission of SARS-CoV-2 Omicron Variant, South Korea, 2021. Omicron is swifter still, with an incubation period of roughly three days, according to a recent C.D.C. MMWR Morb Mortal Wkly Rep. Mar 4 2022;71(9):335-340. doi:10.15585/mmwr.mm7109a2, Burki TK. BMC Med 2021;19:94. EClinicalMedicine. Underlying Medical Conditions and Severe Illness Among 540,667 Adults Hospitalized With COVID-19, March 2020-March 2021. 2021;56(6):1342-1356. doi:10.1002/ppul.25344, Rubens JH, Akindele NP, Tschudy MM, Sick-Samuels AC. Landon E, Bartlett AH, Marrs R, Guenette C, Weber SC, Mina MJ. References to non-CDC sites on the Internet are In summary, our results indicate that the SARS-CoV-2 Omicron BA.5 subvariant has a shorter incubation period than other variants. Characteristics of Adult Outpatients and Inpatients with COVID-19 - 11 Academic Medical Centers, United States, March-May 2020. Our results might warrant a reduction of the quarantine period from 7 to 5 days during the BA.5dominant period in Japan (13). ** Based on CDC analysis of the sequences currently available, and accounting for clustering, CDC estimates a 95% chance of detecting the Omicron variant if it accounted for 0.03% of circulating SARS-CoV-2 lineages during the week ending November 13 and for 0.05% of circulating lineages during the week ending November 20 (4). Suggested citation for this article: . Reducing travel-related SARS-CoV-2 transmission with layered mitigation measures: symptom monitoring, quarantine, and testing. But it would help explain the variant's rapid spread. Jul 2022;6(7):459-465. doi:10.1016/s2352-4642(22)00100-6, Belay ED, Godfred Cato S, Rao AK, et al. On November 26, a Presidential Proclamation suspended entry into the United States for noncitizens (as immigrants and nonimmigrants) who were present in any of eight countries in southern Africa (Botswana, Eswatini, Lesotho, Malawi, Mozambique, Namibia, South Africa, and Zimbabwe) during the 14 days preceding travel to the United States. BMC Pregnancy Childbirth. Frequently asked questions for the B.1.1.529 mutated SARS-CoV-2 lineage in South Africa. The mean and median incubation periods are usually the quick answers, but its also important to know the shape of the curve to understand how many outliers there are and for how long the period is, Stanley H. Weiss, MD, professor of medicine at the Rutgers New Jersey Medical School and professor of biostatistics and epidemiology at the Rutgers School of Public Health, told Verywell. Incubation period correlated with shared meals and adult infectors. doi:10.1136/bmj.o110, Fung M, Babik JM. BNT162b2 mRNA Vaccination Against COVID-19 is Associated with Decreased Likelihood of Multisystem Inflammatory Syndrome in U.S. Children Ages 5-18 Years. National surveillance of bacterial and fungal coinfection and secondary infection in COVID-19 patients in England: lessons from the first wave. Centers for Disease Control and Prevention. As the dominant circulating strain of SARS-CoV-2 evolved from Alpha to Omicron, the incubation period from infection to symptoms or first positive COVID-19 test result gradually decreased, from 5 to 3.4 days, according to a systematic review and meta-analysis published today in JAMA Network Open.. If the pair shared meals on both July 4 and 5, we excluded all data from this pair. Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection: A Systematic Review. The mean incubation period was 2.5 days for patients infected during shared meals, 2.9 days for patients without transmission during shared meals, 3.0 days for patients with infectors who were <19 years of age, and 2.5 days for patients with infectors who were >20 years of age (2.6 days for 79 patients with infectors who were 2059 years of age and 2.1 days for 16 patients with infectors who were >60 years of age). A recent study from the Centers for Disease Control and Prevention (CDC) analyzed data from six people who contracted the Omicron variant of SARS-CoV-2, the virus that causes COVID-19, and found that 73 hours (or three days) was the typical incubation period for patients. Nebraska Cases of Omicron Suggest Short Incubation Period and Possibly Milder Disease. Coagulation abnormalities and thrombosis in patients with COVID-19. Jan 2022;22(1):306-314. doi:10.1111/ajt.16641, Tenforde MW, Patel MM, Gaglani M, et al. Jan 18 2022;327(3):281-283. doi:10.1001/jama.2021.23262, Nygaard U, Holm M, Hartling UB, et al. These cookies may also be used for advertising purposes by these third parties. COVID-19 in Immunocompromised Hosts: What We Know So Far. MMWR Morb Mortal Wkly Rep. Mar 25 2022;71(12):466-473. doi:10.15585/mmwr.mm7112e2, Johnson AG, Amin AB, Ali AR, et al. We fitted incubation period data for each subvariant to the gamma distribution model and calculated parameters and 95% CI within a Bayesian inference framework. Estimating the duration of infectiousness is more challenging than measuring incubation periods; one study that measured viral load of Omicron suggested that viral load had diminished by days 10-13, which is in line with our findings ( 6 ). 2022:o110. Molnupiravir for Oral Treatment of Covid-19 in Nonhospitalized Patients. We defined the patient with the later symptom onset in each pair as the infected patient. of pages found at these sites. Mar 2 2022;376:e068632. 2021;325(11):1074. doi:10.1001/jama.2021.2091, Wanga V, Gerdes ME, Shi DS, et al. . COVID-19 in immunocompromised patients: A systematic review of cancer, hematopoietic cell and solid organ transplant patients. * SIG includes representatives from CDC, the National Institutes of Health (NIH), the Food and Drug Administration (FDA), the Biomedical Advanced Research and Development Authority (BARDA), the U.S. Department of Defense (DoD), the U.S. Department of Agriculture (USDA), and the U.S. Department of Health and Human Services (HHS). If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. Am J Obstet Gynecol. Thank you for taking the time to confirm your preferences. European Journal of Pediatrics. Clin Infect Dis. As a result of the more contagious BA.4 and BA.5 omicron subvariants, COVID-19's incubation period has changed in recent months, Chicago's top doctor previously revealed. More information is available, Travel requirements to enter the United States are changing, starting November 8, 2021.

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